2-CARBOMETHOXY-3-TROPINONE

2-CARBOMETHOXY-3-TROPINONE
2-Carbomethoxytropinone (2-CMT) is a commonly used organic intermediate in the synthesis of cocaine and its analogues. As of at least 1999 no reaction pathway has been discovered that synthesizes cocaine-like compounds without utilizing the reduction of 2-CMT. The structure of cocaine was discovered by Richard Willst?tter in 1898 after he synthesized it from 2-carbomethoxytropinone. Although it was originally believed that 2-CMT in nature was ultimately derived from ornithine and acetic acid, subsequent research has indicated other pathways exist for the biosynthesis of 2-CMT. A ß-keto ester, 2-CMT exists in equilibrium with its keto–enol tautomer.2-CARBOMETHOXY-3-TROPINONE
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Density: 1.173g/cm3
Boiling Point: 294.1oC at 760mmHg
Flash Point: 131.7oC