Studies have shown the risk of a heart attack or stroke for a user of testosterone replacement products nearly doubles when compared to
individuals who don't use these products.
Two studies, a paper published in the medical journal PLOS One as well as a paper published online in the Journal of the American Medical
Association (JAMA), linked testosterone replacement products to
increased risks of cardiovascular events in men.
The study published in the journal PLOS One concluded that men 65 years of age and older who use prescription testosterone therapy
products have twice the risk of a heart attack within the first three
months of using the products.
The JAMA study also found that senior males who use testosterone replacement products are 30% more likely to suffer from a heart attack,
stroke, or death when compared to senior males who do not use the
drugs.The various testosterone therapy replacement manufacturers have
entered into mass tort settlements. In December 2017, Eli Lilly &
Co. agreed to settle 400 federal lawsuits accusing them of
misrepresenting the benefits and risks of their testosterone replacement
products.
In February 2018, Endo Pharmaceuticals Inc., Auxilium Pharmaceuticals, and GlaxoSmithKline LLC agreed to resolve 1,300 federal
lawsuits. In June 2018, Endo Pharmaceuticals announced that it was
allocating $200 million toward settling testosterone therapy cases.
