GW501516: Shocking Secrets About Cardarine RevealedGW-501516 also referred to as Cardarine, is a popular compound that was first developed in the early 1990s. Its main purpose is to prevent the formation of tumors in organs like the prostate, colon and breast tissue.
Although it was developed for a completely different purpose, the bodybuilding community started noticing it as a unique and potentially powerful SARM (Selective Androgen Receptor Modulator).
That's because it has the ability to burn fat, boost endurance and reduce the amount of time that bodybuilders need to recover.
The best part is that GW-501516 is said to not have any side effects.
If all this is true then it's the best thing since sliced bread for the bodybuilding community. But is it all that it's cracked out to be? Let's find out.harmaceutical giant GlaxoSmithKline developed GW501516 with the intention to leverage its benefits for the treatment of blood vessels, heart, and diabetes.
But, research on this SARM stopped during phase 2 because the animals being tested started developing cancer.
The same results haven't been observed in humans however, which means that it's probably only dangerous for animals.
Besides, it would take much longer for the substance to start showing a cancer risk if it were to be tested for that effect on humans.
How was Cardarine discovered, you ask?
Well, the research community has always grappled with trying to find a suitable treatment for lifestyle diseases like inflammation, heart disease, and diabetes.
At some stage, scientists were looking for a compound that would make it possible to increase physical endurance while accelerating the body's fat burning ability. This is when they stumbled upon the PPAR-delta pathway.
They found that by activating this pathway, they could instantly improve endurance, stimulate muscle growth, burn fat and increase energy while decreasing blood lipids.
Cardarine is one of the few compounds that have the ability to bind itself to the PPAR-delta pathway.
It's interesting to note that most of the PPAR-delta is found in the muscles, so activating it naturally leads to:
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