The main adverse effect I would expect to notice with extended modafinil use is insomnia, as modafinil promotes wakefulness. If you have more than a certain amount in your system at the end of the day, you will struggle to get to sleep. If you take a dose of modafinil every 24 hours
https://freemodafinil.com/bitcoin-discount/ , the risk of being unable to sleep will increase. (The half-life of modafinil is 10–12 hours, so after 24 hours you still have up to 25% of yesterday’s dose in the system, and you're adding another 100% today.)