Avanafil is a PDE5 inhibitor medication used to treat erection problems in men. Avanafil comes in tablet form in a variety of doses. You can try - Avana 50 mg Tablet, Avana 100 mg Tablet. Depending on your dosage, this ED medicine will be effective after 15–30 minutes, and research shows it is effective for up to 6 hours. You should not take the dose more than once per day. Do not drink alcohol to excess when taking this medicine. When taken in excess, alcohol can increase your chances of getting a headache or getting dizzy, increasing your heart rate or lowering your blood pressure.