The pharmacological effects of Biligen
[What is Biligen?] The mechanism of Biligen® in the treatment of premature ejaculation (PE) may be related to its inhibition of neuronal reabsorption of serotonin, thereby affecting the potential difference of neurotransmitter acting on cell receptors before and after synapses. Human ejaculation is mainly mediated by the sympathetic nervous system. The reflex pathway of ejaculation comes from the spinal cord reflex center, which is mediated by the brainstem, and the reflex center is initially affected by many brain nuclei (medial preoptic nucleus and inferior paraventricular nucleus). In rats, Biligen® inhibits the ejaculation-driven reflex by acting on the upper level of the spine, where the lateral paragiant cell nucleus (LPGi) is an essential brain structure. The postganglionic sympathetic nerve fibers that innervate the seminal vesicles, vas deferens, prostate, urethral muscles, and bladder neck can make the above-mentioned organs contract to achieve ejaculation. Bilygen® can regulate this ejaculation reflex in rats, thereby prolonging the latency of pudendal motor neuron reflex discharge (PMRD) and reducing the duration of PMRD.[img width=600,height=260]https://pic.pimg.tw/bbergeerlance/1640166712-2820127634-g_n.png?v=1640166712[/img][img width=15,height=15]data:image/gif;base64,R0lGODlhAQABAPABAP///wAAACH5BAEKAAAALAAAAAABAAEAAAICRAEAOw==[/img]?
Indications of Biligen
Biligen is suitable for the treatment of male premature ejaculation (PE) patients aged 18 to 64 who meet all of the following conditions: the penis occurs before, during, or shortly after insertion, and before sexual satisfaction is only caused by minimal sexual stimulation. Continuous or repeated ejaculation; and significant personal distress or interpersonal communication disorder caused by premature ejaculation (PE); and poor ejaculation control ability, short time, I will help you solve it!
[Recommended ordering by Biligen]
Patients with severe premature ejaculation (premature ejaculation symptoms for more than 2 years, love time only 2-3 minutes): 90 capsules
Patients with moderate premature ejaculation (premature ejaculation symptoms for 1-2 years, love time is only 3-5 minutes): 60 capsules
Patients with mild premature ejaculation (premature ejaculation symptoms less than 1 year, love time is only 5-10 minutes): 30 capsules [product specification]: 60mg/1 capsule 1 box of 10 capsules
[Biligen function effect]: Treatment of premature ejaculation, weak ejaculation, and abnormal erection patients
[Shelf life]: 36 months
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[Manufacturer]: Sunrise Pharmaceutical Factory (one of the three largest pharmaceutical factories in India)
?How to use Biligen?
Oral before or after meals. The tablets should be swallowed whole. It is recommended that patients take the medication with at least a full glass of water. Patients should try to avoid injuries caused by prodromal symptoms such as syncope or dizziness.
The recommended first dose for all adult male patients aged 18-64 is 30 mg, which needs to be taken about 1 to 3 hours before sex. If the effect is not satisfactory after taking 30 mg and the side effects are still within the acceptable range, the dosage can be increased to the maximum recommended dose of 60 mg. The recommended maximum dosage is once every 24 hours.
If doctors choose this product to treat premature ejaculation (PE), they should evaluate the risks and benefits reported by the patient in the first 4 weeks after using the drug, or evaluate the patient's risk-benefit balance after using the drug for 6 treatment doses and decide whether to continue using it This product treatment.
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