This paper addresses a number of these difficulties and offers some practical guidelines for successfully completing case study research. The paper focuses on the pragmatics of conducting case study research, and draws from the discussion at a panel session conducted by the authors at the 8th Australasian Conference on Information Systems, from the authors' practical experiences, and from the case study research literature.Observational
zynev studies suggest that the incidence of cardiovascular disease is reduced by about 50% in users of unopposed estrogens, but the reduction may have been overestimated because of a greater tendency for women at lower risk to use estrogens. To minimize bias due to such behavior,
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