wisepoqder Cyclofenil powder (INN, USAN, BAN) (brand names Fertodur, Menopax, Ondonid, Ondogyne,
Sexovid, others) is a selective estrogen receptor modulator (SERM) used
as a gonadotropin stimulant which is or has been marketed in Europe,
South Korea, Mexico, and Brazil, among other countries.
Cyclofenil powder is a gonadal stimulant and inducer of ovulation. It is used in the treatment of infertility and amenorrhea, but is
thought to be less effective than CLOMIPHENE.
05 Cyclofenil powder (2624-43-3) History
Cyclofenil powder (INN, USAN, BAN) (brand names Fertodur, Menopax, Ondonid, Ondogyne, Sexovid, others) is a selective estrogen receptor
modulator (SERM) used as a gonadotropin stimulant which is or has been
marketed in Europe, South Korea, Mexico, and Brazil, among other
countries.
Cyclofenil was first introduced in 1970 under the brand name Ondogyne in France. Subsequently, it was introduced under the brand
names Sexovid in Japan in 1972, Ondonvid in the United Kingdom in 1972,
and Fertodur in West Germany in 1972 and Italy in 1974. It was also
marketed as Sexovid in Sweden, Neoclym in Italy, and Klofenil in Turkey.
Cyclofenil was studied in the 1970s as an agent to induce ovulation in infertile women. It was then investigated as a possible treatment for
scleroderma in the 1980s, but was found to be ineffective. Later study
of its efficacy in treating Raynaud’s phenomenon in people with
scleroderma also found no statistically significant benefit.
Cyclofenil powder is a nonsteroidal antiestrogen that is used in the treatment of menstrual disturbances and anovulatory infertility due to
hypothalamic-pituitary insufficiency
Cyclofenil is an analytical reference standard categorized as an anti-estrogen. 1,2 Anti-estrogens, including cyclofenil, have been used
as performance-enhancing drugs in sports doping. This product is
intended for research and forensic applications
