Hi Friends, as u all know that I am a Doctor. I am qualified Practitioner of Homoeopathy. If you or anyone of your family, have some health problems and want Homeopathic treatment then you can tell me. I’ll be there for your help.
I will try to post here some information about the diseases or other problems, for your knowledge. I hope you will be like it.
Depends upon the Stage at which the individual etiologic agent acts in Normal fat transport and metabolism
--Lipid Source-- 1. From Diet as Chylomicrons (Triglycerides and Phospholipids) and Free Fatty Acids 2. From Adipose Tissue as Free Fatty Acids 3. From Acetate of Liver Cells Most of the Fatty Acids is esterified into Triglycerides by Alpha Glycerophosphate and small part of Free Fatty Acid is Changed into Cholesterol, Phospholipds, Ketone Bodies.
Lipoproptien is the Form of Lipid excreted by Hepatocytes.
Fatty Liver occurs on excessive accumulation of Triglycerides which can occur by
1. Increased entry of Free Fatty Acids into Liver. 2. Increased synthesis of Free Fatty Acids by Liver. 3. Decreased conversion into Ketone Bodies thus, increased formation of Triglycerides. 4. Increased alpha glyceroPhosphate causing increased esterification of fatty acids to Triglycerides. 5. Decreased synthesis of Lipo Amino Protien - decreased formation of Lipoprotien from Triglycerides. 6. Block in excretion of Lipoprotien from the Liver into Plasma.
--Pathological Changes--
Gross -
1. Enlarged with a tense, glistening capsule and rounded margins 2. Cut surface bulges slightly and is pale yellow to yellow. 3. Greasy to tuch
-Microscopically - 1. Numerous lipid vacuoles in the cytoplasm of Hepatocytes. 2. Initially small and present around the nucleas which progress. 3. May contain Lymphocytes, Macrophages, multinucleated giant cells.
Demonstration by Frozen section followed by fat stains like
1. Sudan Dyes - Sudan III, Sudan IV, Sudan Black. 2. OilRed O 3. Osmic Acid
--Clinical Features of Fatty Liver--
1. Often no symptoms or Signs 2. Vague Abdominal symptoms of nausea, vomiting and Diarrhoea. 3. Chronic Liver Disease.
--Investigations--
1. Elevated MCV - Heavy Drinking 2. Liver Biochemistry - Mild Abnormalities with elevation of Serum Amino Transferase enzyme. 3. Gamma GT levels - Sensitive test to determine whether patient is taking Alcohol 4. Changes in All Liver Biochemical Parameters - - Severe Fatty infiltration - Determined by USG, CT Scan, Liver Histology
--Management and Prognosis--
-General Management- - Advise to Stop drinking. - Delerium Tremens (Give Diazepam) - Intravenous Thiamine to prevent Wernick-Korsakoff' s Encephalopathy - Bed Rest - Protein Rich diet and Vitamins supplement.
Age: 124
7071 days old here
Total Posts: 51848
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Location:
Pakistan, Pakistan
"Excessive computer use 'threat to eyesight'"
Watching a computer screen for nine or more hours a day might be linked to a progressive eye disease that can blind without treatment, researchers warned yesterday.
The risk of developing glaucoma this way was highest for those with short sight, they said in a study which provided more bad news for male office workers and professionals.
They were told by New York eye specialists last year that wearing a tightly knotted tie could make the condition more likely.
The potential dangers of the booming use of new technology in the office and at home were outlined by researchers at the Toho University school of medicine in Tokyo, Japan, in the Journal of Epidemiology. They tested 10,000 workers with an average age of 43 as part of a general medical check-up as well as collecting their histories of computer use and eye disease.
Just over 5% had visual field abnormalities and there appeared to be a significant link between these and heavy computer use among those with long or short sight. But detailed eye tests revealed that a third of these had suspected glaucoma, and this was more obvious in those with myopia.
A link with short sight has already been established for glaucoma, a disease in which fluid cannot flow out of the eye because meshwork in the coloured part, the iris, has become blocked. Pressure then builds up, threatening damage to nerve fibres in the back of the eye and the optic nerve.
But the added ingredient of heavy computer use, while long debated as a possible risk factor for short sight, has not been studied for glaucoma, according to David Wright, chief executive of the International Glaucoma Association (IGA), who said the researchers "have provided a fascinating study that needs to be followed up".
About 2% of people over 40 develop glaucoma, which if diagnosed early can usually be treated with eyedrops. "Anyone over 40 should have regular, routine and comprehensive eye tests," said Mr Wright.
There were comparatively few women in the Japanese study because men comprise most of the workforce there. The researchers also said it was difficult to establish exactly who might have had a family history of glaucoma because it often went undiagnosed for a long time.
They suggested, however, that the optic nerve in myopic eyes might be much more susceptible to computer stress. "Computer stress is reaching higher levels than has ever been experienced before. In the next decade, therefore, it might be important for public health professionals to show more concern about myopia and visual field abnormalities in heavy computer users."
The type of chronic glaucoma that was a concern in the Japanese study is the most prevalent in Caucasian and African-Caribbean populations.
Close blood relatives of people who have glaucoma are at far higher risk, and the IGA says such people should be tested from the age of 35, rather than 40. For African-Caribbeans, for whom the risk is four times as high as whites, or for those with diabetes, testing should be done even earlier.
If the condition is advanced, or drops fail to reduce eye pressure, surgery might be needed to make an extra drainage channel in the white of the eye. Alternatively, laser treatment might be used to improve the flow of fluid through the meshwork around the iris.
Age: 124
6570 days old here
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A Gene That Controls Fat Mobilisation and Possibly Prolongs Lifespan ------------------------------------------------------------ --------
In a recent study, scientists from the Department of Biology at MIT discovered that the SIRT1 gene, which is associated with longer life span, may also be linked to a pathway that reduces the level of cholesterol in the body.
The researchers found that this gene activates a cellular pathway that flushes out cholesterol from the body using high density lipoprotein (HDL) or "good" cholesterol.
They showed that low SIRT1 levels in mice resulted in accumulation of cholesterol in cells such as macrophages. This was due to reduced activity of the liver X receptor (LXR) protein, which is responsible for transporting cholesterol out of macrophage cells. SIRT1 is a positive regulator of LXR as it promotes deacetylation and subsequent ubiquitination. Studies have also shown that loss of SIRT1 in vivo reduces the expression of a variety of LXR targets involved in lipid metabolism.
This discovery has great potential to enable researchers to design drugs that could lower the risk of diseases associated with high cholesterol, such as atherosclerosis and Alzheimer's disease.
Age: 124
7767 days old here
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Lahore, Pakistan
Influenza (say: in-floo-en-zah) is also called the flu. It's an infection that causes fever, chills, cough, body aches, headaches, and sometimes earaches or sinus problems. The flu is caused by the influenza virus (say: vy-rus). A virus is a microorganism (say: my-croh-or-gah-nih-zum), which means it's so small that you can't see it without a strong microscope.
For most people, the flu is a drag, but it goes away in a week or two. But for some people, the flu can make them very sick. Those groups include:
babies and kids under age 5 people older than 50 adults and kids who have health problems, such as diabetes and asthma Anyone who's at risk of getting really sick needs to get a flu shot, or vaccine (say: vak-seen). People such as doctors and nurses also need the shot because they take care of sick people, and it's good for anyone who is around older people and younger kids to get the vaccine.
And now, experts say that all kids between the ages of 6 months and 18 years should get the flu shot. This is especially important for kids who have:
heart or lung disorders, including asthma chronic diseases such as diabetes, kidney disease, certain kinds of anemia, or immune system problems, including HIV/AIDS Flu vaccines are usually given in the fall, before flu season starts. Flu season means the months of the year when a lot of people have the flu and it's easy to catch it. It starts in November and usually ends in April.
Age: 124
7767 days old here
Total Posts: 26285
Points: 0
Location:
Lahore, Pakistan
How Does the Flu Spread? This virus gets around in little drops that spray out of an infected person's mouth and nose when he or she sneezes, coughs, or even laughs. You can catch the flu from someone who has it if you breathe in some of those tiny flu-infected drops. You can also catch the flu if those drops get on your hands and you touch your mouth or nose. No wonder people are always saying to cover your mouth when you sneeze!
What If You Get the Flu? But even if you get a flu shot, steer clear of sneezers, and you wash your hands regularly, you still might get the flu.
At the doctor's office, the doctor will ask you how you've been feeling and examine you. He or she might use a long cotton swab to get a sample of the gunk in your nose or throat. Testing this sample in a lab can determine, for sure, that you have the flu. But usually this isn't necessary. Based on your symptoms, your doctor can usually tell if you have the flu, especially during times when a lot of flu is going around your town.
Once your doctor says you have the flu, you can start taking these steps to feel better:
Rest in bed or on the couch. Drink lots of liquids, like water, chicken broth, and other fluids. Take the medicine your mom or dad gives you to ease your fever, aches, and pains. Tell your mom or dad if you have trouble breathing, your muscles really hurt, or if you feel confused. These are signs you may need to see the doctor again. Most of the time, you'll feel better in a week or two. Until then, you'll have to stay home from school and take it easy. We hope you're flu-free this year, but if you do get the flu, now you know what to do!